RNA structural analysis by evolving SHAPE chemistry
نویسندگان
چکیده
منابع مشابه
Structural Chemistry of Human RNA Methyltransferases.
RNA methyltransferases (RNMTs) play important roles in RNA stability, splicing, and epigenetic mechanisms. They constitute a promising target class that is underexplored by the medicinal chemistry community. Information of relevance to drug design can be extracted from the rich structural coverage of human RNMTs. In this work, the structural chemistry of this protein family is analyzed in depth...
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ژورنال
عنوان ژورنال: Wiley Interdisciplinary Reviews: RNA
سال: 2014
ISSN: 1757-7004
DOI: 10.1002/wrna.1253